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STRASS 2 is an international randomised trial with stratification by specific tumour histology, including only high-grade de-differentiated liposarcoma and leiomyosarcoma. The primary objective will be to assess whether three cycles of preoperative chemotherapy improve disease-free survival compared to surgery alone.

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    Background: Unlike for extremity sarcomas, the efficacy of radiotherapy for retroperitoneal sarcoma is not established. The aim of this study was to evaluate the impact of preoperative radiotherapy plus surgery versus surgery alone on abdominal recurrence-free survival.

    Strass fransar 1 gård

  • STRASS II is a pan-European (13 countries) study with a transatlantic collaboration with multiple specialized sarcoma centers in Australia, Canada and North America. This collaboration recently completed inclusion of the first randomized controlled trial in retroperitoneal sarcoma ever, the STRASS trial examining the role of pre-operative radiotherapy in these tumours.

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    The grant is to run the international trial in Australia – “A randomised phase III study of neoadjuvant chemotherapy followed by surgery versus surgery alone for patients with High Risk RetroPeritoneal Sarcoma (STRASS 2)”.
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      Retroperitoneal sarcoma are often large tumors located at the back site of the abdomen. It is rare cancer with around 7 new cases per 100.000 inhabitants per year. It occurs mostly from the age of 40 upwards until the age of 80 or higher, and around 25% of all patients pass away eventually from the disease.



    The EORTC STRASS II trial is a multi-national phase 3 clinical trial taking place in ten European countries, the UK and a collaboration with multiple specialized sarcoma centres in Australia, Canada and North America, investigating treatment options for this sarcoma.

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    A prospective registry has been started and a new randomized trial, STRASS-2, is in preparation to analyze the role of neoadjuvant chemotherapy for high-grade liposarcoma and leiomyosarcoma of the retroperitoneum. Summary: Collaboration is critical to study a rare disease like RPS.

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    Märke: BluKids. Typ: Sweatshirt, strass, fransar. Färg: svart. Strl: Material: Bomull/Elastan. Mått, armhåla-armhåla: cm, plagglängd: cm. Skick/Övrigt: Fint beg skick. Betalning: Betalning med Swish.